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"What we are giving essentially is a living drug" permanently altered cells that multiply in the body into an army to fight Adidas Tracksuit Blue Womens
In one study, all five adults and 19 of 22 children with acute lymphocytic leukaemia, or ALL, had a complete remission, meaning no cancer could be found after treatment, although a few have relapsed since then.
The treatment involves filtering patients' blood to remove millions of white blood cells called T cells, altering them in the lab to contain a gene that targets cancer, and returning them to the patient in infusions over three days.
Results on other patients with myeloma, lymphoma and chronic lymphocytic leukaemia, or CLL, will be reported at the hematology group's conference that starts on Saturday in New Orleans.
A few patients with one type of leukaemia were given this one time, experimental therapy several years ago and some remain cancer free today. Now, at least six research groups have treated more than 120 patients with many types of blood and bone marrow cancers, with stunning results.
Gene therapy used Adidas Hoodie With Zipper
Cancer was so advanced in eight year old Emily Whitehead of Philipsburg, Pennsylvania, that doctors said her major organs would fail within days. She was the first child given the gene therapy and shows no sign of cancer today, nearly two years later.
the cancer, said Dr David Porter, a University of Pennsylvania scientist who led one study.
Talking with the researchers, "there is a sense of making history . a sense of doing something very unique," said Herv Hoppenot, president of Novartis Oncology, the division leading the work.
to fight cancer
These were gravely ill patients out of options. Some had tried multiple bone marrow transplants and up to 10 types of chemotherapy or other treatments.
Several drug and biotech companies are developing these therapies. Penn has patented its method and licensed it to Switzerland based Novartis AG. The company is building a research centre on the Penn campus in Adidas Sweatshirt Mens Black
Doctors say this has the potential to become the first gene therapy approved in the United States and the first for cancer worldwide. Only one gene therapy is approved in Europe, for a rare metabolic disease.
"It's really exciting," said Dr Janis Abkowitz, blood diseases chief at the University of Washington in Seattle and president of the American Society of Hematology. "You can take a cell that belongs Men Adidas Sweatshirts to a patient and engineer it to be an attack cell."
Philadelphia and plans a clinical trial next year that could lead to federal approval of the treatment as soon as 2016.
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