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have shown it has an effect, and we have shown it has an effect at a very, very low concentration. Babies are the most susceptible because this particular gene is heavily, heavily present in the placenta. tests could show a mother had low and acceptable levels of PBA, her placenta and foetus could be heavily affected, Dr Gibert said.
This meant ERR was 1000 times more potent, Dr Gibert said.
BPA is banned in many parts of the world and in Australia there has been a voluntary move away from using BPA in baby bottles, the plastics industry has started using other bisphenol compounds, Dr Gibert said.
Dr Gibert said the results of the study had strengthened his resolve to reveal the true health impacts of BPA and other bisphenol derivatives, BPS and BPAF.
children and adults have enzymes that protect our bodies from the effects of BPA. However, embryos and babies have not yet developed these enzymes, making them highly susceptible to BPA, Dr Gibert said.
while the pregnant mother is herself protected by the enzyme, it is her unborn child that is susceptible due to the BPA collecting in, and passing through, the placenta, leading to potential development issues in the foetus issues that could carry with the baby throughout its life. Deakin scientists are part of an international team led by Professor Vincent Laudet at the Institute of Functional Genomics of Lyon in France, which has discovered a new pathway for BPA to spread through the body via a protein known as ERR (oestrogen related receptor).
has looked at the health impacts of these other bisphenols, which could be as dangerous as BPA. This is why we are including them in our research. google_ad_section_end(name=story_body) >
know that there are links between BPA exposure and diabetes and obesity but we do not know how it works. With what we have discovered about this new receptor we may well have found the missing link, Dr Gibert said.
Geelong scientist calls for urgent law reform on plastics to protect Aussie babies
the possibility BPA could be a cause of obesity and diabetes.
The Deakin research was also exploring the metabolic effects of exposure to BPS and BPAF during embryo formation and development, he said.
is time for Australia to re evaluate the use of BPA and follow the lead of Europe, the US and Canada where the product is banned, Dr Gibert said.
parts of world, alarmingly, they were still allowed in Australia.
While current Australian guidelines stated it was safe to ingest up to 50 micrograms of BPA per day, new research showed this was not the case and the guidelines urgently needed to change, he said.
is possible that exposure to bisphenols before birth could cause developmental issues that predispose children to obesity and diabetes, which is the focus of our current research. It has also been shown that BPA can accumulate in the placenta and pass on to the embryo.
that with a low dose of BPA you could have a dramatic effect on this particular target and the problem is, this particular target is heavily present in pregnancy, he said.
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Dr Gibert said the receptor played an important Adidas Sweatshirt Maroon
BPA could leak from plastic containers or bottles into food or drink, particularly when heated, Dr Gibert said.
now it was believed that BPA only affected oestrogen receptors and therefore only had an impact on this hormone function. Now that we have found this new receptor we can expand the targets of further research to developmental effects and metabolism. results of the study, published in The Journal of the Federation of American Societies for Experimental Biology, added to the growing body of international evidence of the health risks associated with BPA. These included breast cancer, reproductive disorders, brain function and inner ear development, he said.
Deakin University Metabolic Research Unit scientist, Dr Yann Gibert, said the while biphenols (BPA) were banned in most Blue Adidas Hoodies
The Deakin research found ERR was 1000 times more sensitive to BPA than oestrogen receptors, he said.
need to rethink the tolerable daily intake as BPA will induce effects at a lower dose than currently acknowledged. In Europe this is already happening with Adidas Pullover Half Zip the intake soon to be dropped to 5 micrograms per kilo per day, he said.
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