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Gaining a better understanding of how this mutation triggers feelings of pleasure and gratification at the sight of high calorie foods like chocolate could help improve strategies designed to prevent overeating, the scientists suggested. adults are obese. Obesity is typically caused by a combination of overeating, a lack of physical activity and genetics. The most common genetic cause of obesity is a mutation in the melanocortin 4 receptor (MC4R) gene, the British researchers explained.
WEDNESDAY, July 30, 2014 (HealthDay News) Some obese people have a genetic mutation that seems to ramp up the reward centers in their brains when they see food, researchers report.
light up when people with the mutation and normal weight people Adidas Hoodie White Womens
did not have the same level of response," lead researcher Dr. Agatha van der Klaauw, of the Wellcome Trust MRC Institute of Metabolic Science at Addenbrooke's Hospital in Cambridge, England, said in an Endocrine Society news release.
viewed pictures of appetizing foods. But overweight people without the mutation Adidas Velvet Tracksuit
In conducting their study, published July 30 in the Journal of Clinical Endocrinology Metabolism, the scientists compared eight people who were obese and had the MC4R gene mutation with 10 people Adidas Hoodie Grey And White who were overweight or obese who did not have the gene mutation, and eight people who were a normal weight. Their response to photos of appetizing foods was then compared to the effect of pictures of bland foods, such as rice or broccoli, and objects like staplers.
"For the first time, we are seeing that the MC4R pathway is involved in the brain's response to food cues and its underactivity in some overweight people. Understanding this pathway may help in developing interventions to limit the overconsumption of highly palatable foods that can lead to weight gain," she explained.
Gene Mutation May Make Food More Tempting
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Surprisingly, participants who were the same age and weight had different responses to pictures of appetizing foods, the researchers found. The brain scans revealed that obese people with the genetic mutation and participants who were a normal weight had similar heightened activity in the reward centers of their brain. Meanwhile, the reward centers in the obese and overweight people who did not have the genetic mutation were underactive.
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